Mahesh Bhupathi and Mark Knowles were beaten in the final of the Pilot Pen men's doubles tournament on Saturday night.
The second seeded Indo-Bahamian pair lost to Brazillians Marcelo Melo and Andre Sa 5-7, 2-6.
The fourth seeded Brazilians, who did not lose a set in all their four matches in the tournament, earned $36,500 for their triumph.
Croatia's Marin Cilic defeated America Mardy Fish to win the $708,000 men's singles event, a final US Open tune-up.
The sixth-seeded Cilic won 6-4, 4-6, 6-2 in just under two hours.