Igor Andreev tamed a leaping Marcos Baghdatis with a 2-6, 6-1, 6-3, 6-4 win to reach the quarter-finals of a Grand Slam for the first time.
The unseeded Russian will be heading into uncharted territory after adding the 16th-seeded Cypriot to his list of high-profile victims in Paris.
Men's singles quarter-final line-up
Roger Federer vs Tommy Robredo
Rafael Nadal vs Carlos Moya
Nikolay Davydenko vs Guillermo Canas
Novak Djokovic vs Igor Andreev
The conqueror of Andy Roddick in the first round, Andreev took his time to find his range on Suzanne Lenglen court but it was not long before Baghdatis was left attempting futile jumps in the air as he tried to chase down the Russian's soaring winners.
A final mishit shot into the stands ended Baghdatis's challenge and put Andreev into the last eight against sixth seed Novak Djokovic.
Results:
Men's singles fourth round: Rafael Nadal (Spain) beat Lleyton Hewitt (Australia) 6-3, 6-1, 7-6(5); Igor Andreev (Russia) beat Marcos Baghdatis (Cyprus) 2-6, 6-1, 6-3, 6-4, Novak Djokovic (Serbia) beat Fernando Verdasco (Spain) 6-3, 6-3, 7-6(1); Carlos Moya (Spain) beat Jonas Bjorkman (Sweden) 7-6(5), 6-2, 7-5.