Moderna's vaccine shows protection from COVID-19 in monkey study
July 29, 2020  13:36
US biotechnology company Moderna's experimental vaccine to prevent COVID-19 induced robust immune responses and rapidly controlled the novel coronavirus in the upper and lower airways of monkeys exposed to SARS-CoV-2, according to a study.
 
The candidate vaccine, mRNA-1273, has been co-developed by scientists at Moderna and the National Institute of Allergy and Infectious Diseases  in the US.
The study, published in the New England Journal of Medicine, complements recently reported interim results from an NIAID-sponsored Phase 1 clinical trial of mRNA-1273.
In the study, three groups of eight rhesus macaques received two injections of 10 or 100 microgrammes of mRNA-1273 or a placebo. Injections were spaced 28 days apart.
Vaccinated macaques produced high levels of neutralising antibodies directed at the surface spike protein used by SARS-CoV-2 to attach to and enter cells, the researchers said.
-- PTI
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