Cancers 'Achilles heel' identified

September 11, 2012 10:42

Scientists at Mount Sinai School of Medicine have made a breakthrough that could lead to the development of new tests for early cancer diagnosis, prognostic tests, and innovative therapeutic strategies.

They have discovered a sub-population of cells that display cancer stem cell properties and resistance to chemotherapy, and participate in tumor progression.

Resistance to chemotherapy is a frequent and devastating phenomenon that occurs in cancer patients during certain treatments. Unfortunately, tumours that initially respond to chemotherapy eventually become resistant to it, contributing to tumour progression and death.

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